Inconsistent GLP-1 use may blunt weight-loss benefits, Penn study suggests
TL;DR Summary
A Penn study in mice indicates that cycling GLP-1 weight-loss drugs like semaglutide on and off could trigger weight and fat gain and reduce drug effectiveness, highlighting consistency as a key takeaway, though it’s not yet proven in humans and more research is needed on other GLP-1 meds like Zepbound.
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