The Science of Ageing: Caloric Restriction and Research Advances

Research on calorie restriction and nutrient signalling pathways has shown promising results in extending lifespan and combating ageing in animals. However, maintaining strict calorie-restricted diets is challenging for humans. Scientists are now exploring alternative methods to activate these pathways, such as using drugs like rapamycin and metformin, which have shown potential in extending lifespan in lab animals. Other substances like taurine and NAD+ have also demonstrated positive effects on longevity. The study of these pathways and potential interventions offers hope for finding ways to slow down the ageing process in humans.