New Clothes, New Irritations: Washing Helps, But Some Chemicals Persist

TL;DR
New clothes can irritate skin due to substances like dyes (often azo dyes), fragrances, finishing agents, formaldehyde, and pesticides, especially in areas of friction. A cold rinse can remove much of these irritants, reducing exposure to dyes and fragrances, but some chemicals (e.g., flame retardants and antimicrobial finishes) may linger after multiple washes. For dry-clean-only items, steaming or airing out can help odors, and a barrier layer can be worn underneath; if a rash persists, consult a dermatologist. Most reactions are irritant dermatitis and short-lived, though allergic dermatitis can develop with repeated exposure. Washing may also affect collar stiffness and color vibrancy.
Do You Really Need to Wash New Clothes Before Wearing Them? The New York Times
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