Non-smoker with incurable lung cancer defies odds with targeted therapy and brain treatments

A UK woman, Jade Fardon, diagnosed in 2022 at age 29 with stage IV ALK-positive lung cancer despite never smoking, was treated with a targeted drug that shrank tumors. She later developed brain metastases requiring gamma knife radiotherapy and brain surgery, and after progression she switched to new medication and ongoing monitoring. She remains active in work and fundraising while raising awareness that lung cancer can affect young, non-smokers.