How Ultraviolet Light Affects Precancerous Cells' Evolution

Ultraviolet light exposure triggers DNA damage in immune cells that migrate through the skin, leading to the accumulation of mutations associated with the transformation to malignancy, according to a study published in Nature. The research sheds light on the development of an aggressive form of leukemia called blastic plasmacytoid dendritic cell neoplasm (BPDCN), which is often diagnosed by the presence of malignant cells in the skin.