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Skin

All articles tagged with #skin

Modest but Real Gains from Collagen Supplements, Large Review Finds
health13 days ago

Modest but Real Gains from Collagen Supplements, Large Review Finds

A large synthesis of 113 clinical trials and 16 systematic reviews (nearly 8,000 participants) finds collagen supplements offer modest but real benefits: improvements in muscle health and osteoarthritis pain, plus better skin hydration and elasticity with consistent, longer-term use. However, results vary by product type, dose, and study quality, and many trials are short or poorly designed, leaving long-term effects and who benefits most still unclear; more standardized research is needed.

Skin’s cellular map reveals TNF-driven immune–fibroblast networks in SALT-like neighborhoods
science19 days ago

Skin’s cellular map reveals TNF-driven immune–fibroblast networks in SALT-like neighborhoods

Researchers generated an organ-wide, MERFISH-based single-cell spatial atlas of about 1.2 million cells from normal adult human skin, spanning 15 body sites and 22 donors, resolving 45 cell types and 10 multicellular neighborhoods. They highlight a perivascular neighborhood reminiscent of skin-associated lymphoid tissue (SALT) where TNF coordinates immune–fibroblast crosstalk, with CCL19+ fibroblasts proximal to vessels playing a central role. By integrating MERFISH with scRNA-seq and Visium data, they map site-specific cellular compositions, neighborhood dynamics, and ligand–receptor signaling, and show pan-disease immune alterations in the perivascular niche across skin conditions. An interactive web tool is provided to explore these data, underscoring spatial organization as a key driver of skin biology and disease.

Collagen Delivers Skin and Joint Wins, But Not a Workout Miracle
health25 days ago

Collagen Delivers Skin and Joint Wins, But Not a Workout Miracle

A large review of 113 trials (about 8,000 participants) finds collagen can modestly improve skin hydration and elasticity and reduce osteoarthritis joint pain with consistent, long-term use, plus small gains in lean mass. It does not enhance post-exercise recovery or tendon properties, and effects on blood pressure, cholesterol, blood sugar, or oral health are inconclusive. Collagen is not a miracle cure and should be used with realistic expectations and medical guidance.

Why Aging Odor Happens—and How to Minimize It
health1 month ago

Why Aging Odor Happens—and How to Minimize It

A real aging odor is produced by 2-nonenal, a fatty aldehyde whose production increases with age as skin antioxidant defenses decline, sebum changes, and environmental stress accumulate; the scent typically appears after age 40 and is more noticeable in the 50s, though it varies by genetics, skin type, and lifestyle. It clings to skin and fabrics and isn’t easily washed away, and while some people may not notice it themselves due to olfactory adaptation, there’s no proven cure. Experts suggest skincare with antioxidants and practices that reduce aldehyde persistence (like certain tannin-containing cleansers) and careful laundering to minimize the odor, framing aging as a natural change rather than a hygiene problem.

Collagen May Improve Elasticity, But Won’t Prevent Wrinkles
health1 month ago

Collagen May Improve Elasticity, But Won’t Prevent Wrinkles

A review of 113 trials with about 8,000 participants finds daily collagen can improve skin elasticity and hydration over time but does not prevent wrinkles; it may also ease joint pain, though it is not a cure-all. Benefits come with consistent use and vary by supplement type (marine, bovine, vegan) with no clear winner. Diets rich in vitamin C and zinc support collagen production, and more dermatology-focused studies are needed to confirm these effects.

New Dinosaur Haolong dongi Wore Hollow, Porcupine-Like Spikes
science1 month ago

New Dinosaur Haolong dongi Wore Hollow, Porcupine-Like Spikes

Scientists describe Haolong dongi, a juvenile iguanodontian from northeastern China, with hollow, porcupine-like spikes along its neck, back, and sides. The 2.45 m skeleton is exceptionally well-preserved, but the spikes’ purpose remains unclear—defense, display, or sensing—while pigment was not detected and they are not protofeathers. The discovery broadens our view of dinosaur skin and was published in Nature Ecology & Evolution (2026).

Serine Shortage Reprograms Hair Follicle Stem Cells for Faster Wound Healing
science2 months ago

Serine Shortage Reprograms Hair Follicle Stem Cells for Faster Wound Healing

Rockefeller University researchers found that when serine levels drop, the integrated stress response activates and hair follicle stem cells reduce hair production to prioritize skin repair, speeding wound healing; boosting serine has limited effect due to the body's tight control over its circulation, though restoring serine in cells lacking it can partly rescue hair growth—pointing to diet or drug strategies to modulate serine/ISR for faster healing.

"Decoding Hidden Health Issues Through Your Skin: What Your Dermatologist Can Uncover"
health2 years ago

"Decoding Hidden Health Issues Through Your Skin: What Your Dermatologist Can Uncover"

The skin, being the largest and most visible organ, can offer insight into our overall health. Various rashes and skin changes can indicate underlying illnesses such as Lyme disease, blood vessel issues, metabolic disorders, and heart conditions. Recognizing these skin signs and seeking medical attention when necessary can help in early diagnosis and treatment of potentially serious health issues.

"Discovery of 290-Million-Year-Old Reptile Skin Fossil in Oklahoma Cave"
paleontology2 years ago

"Discovery of 290-Million-Year-Old Reptile Skin Fossil in Oklahoma Cave"

Paleontologists have discovered a 290 million-year-old skin fossil in an Oklahoma cave, making it the earliest known example of a fossil from an amniote. The fossil is believed to have come from a reptile with a rough skin surface similar to that of a crocodilian animal. The discovery is significant for understanding the evolutionary history of animals, as skin fossils are rare due to their fragility. The cave's unique conditions, including soft sediment and a lack of oxygen, contributed to the preservation of the skin fossil. Although no nearby skeleton was found, the discovery provides valuable insights into prehistoric life.

"Oldest Fossilized Skin Unearthed: 289-Million-Year-Old Discovery"
science2 years ago

"Oldest Fossilized Skin Unearthed: 289-Million-Year-Old Discovery"

Scientists have discovered the oldest-known piece of fossilized skin, a pebbly scrap from a 289 million-year-old reptile, offering rare insight into the evolution of skin. The specimen was found in the Richards Spur limestone cave system in Oklahoma, preserved by ideal conditions including rapid burial, low oxygen levels, and hydrocarbons from an oil seep. The texture of the skin resembles that of a crocodile, providing valuable clues to how skin evolved in ancient reptiles.

"300-Million-Year-Old Fossilized Skin Unearthed in Oklahoma Quarry"
paleontology2 years ago

"300-Million-Year-Old Fossilized Skin Unearthed in Oklahoma Quarry"

Researchers have discovered the world's oldest known fossilized skin, dating back around 289 million years, from a species of reptile that predates dinosaurs. The skin fragment, found in an Oklahoma limestone cave, is at least 130 million years older than the previous oldest known skin fossil. The sample, resembling crocodile skin with hinged regions similar to snakes and worm lizards, provides insight into the evolution of terrestrial animals and the importance of the epidermis as a barrier between internal body processes and the external environment. The study was published in the journal Current Biology.