Herbal boost: Basil extract eases depression and anxiety when added to antidepressants

In a randomized, single-blind trial, 60 adults with major depressive disorder and concurrent anxiety received sertraline plus either 1100 mg of dried basil leaf extract nightly or a placebo for four weeks. The basil group showed greater symptom reductions on both the Beck Depression Inventory and the Hamilton Anxiety Rating Scale, with depression dropping from about 39 to 21 and anxiety from about 33 to 13, compared with placebo reductions to roughly 30 and 25, respectively. Basil was well tolerated, but the study’s short duration and single-blind design mean longer-term effects and causality require further research; basil should be viewed as an add-on, not a replacement for standard care.