Tag

Depression

All articles tagged with #depression

Humboldt County Expands Access to Noninvasive TMS for Depression
health17 hours ago

Humboldt County Expands Access to Noninvasive TMS for Depression

Two Humboldt County clinics have begun offering FDA-approved Transcranial Magnetic Stimulation (TMS) for major depressive disorder and related conditions, improving local access by reducing the need to travel to the Bay Area or Chico. Humboldt Counseling Connection in Eureka started Aug. 25 with 16 patients, while the Center for New Growth in Arcata will begin with about 6 patients on Sept. 1. TMS is non-invasive, typically 30 sessions over seven weeks, and insurance coverage is available (Medi-Cal/Partnership and private plans at HCC; Medicare/Partnership/VA at Center for New Growth). The move aims to address local mental-health gaps in a county with high ACEs and suicidality.

Depression May Stop New Brain Cells From Forming in Adults, Altering Memory
health-and-medicine19 hours ago

Depression May Stop New Brain Cells From Forming in Adults, Altering Memory

A large Columbia-led study shows major depressive disorder disrupts neurogenesis in the adult hippocampus, potentially impairing pattern separation and the ability to store distinct memories. The researchers mapped widespread molecular and epigenetic changes across the hippocampal network, linking inflammation and altered gene programs to depression and suggesting new targets for treatments that classify depression by molecular subtype rather than brain region.

Hippocampal Neurogenesis Halts in Adults with Major Depression
health1 day ago

Hippocampal Neurogenesis Halts in Adults with Major Depression

Columbia University researchers link major depressive disorder to stalled adult hippocampal neurogenesis, showing reduced neuron birth impairs pattern separation and emotional memory. Post-mortem analysis of about half a million brain cells reveals gene and epigenetic changes, including inflammation, pointing to neurogenesis as a therapeutic target and suggesting depression could be classified by molecular features rather than brain region.

Anna Faris says sobriety helped end self-sabotage and improve mood
entertainment6 days ago

Anna Faris says sobriety helped end self-sabotage and improve mood

On the Dear Chelsea podcast, Anna Faris revealed she stopped drinking in the past year, calling sobriety a gift that helped her stop self-sabotage and noting a link between alcohol and depression for her. She also credited hormone patches for mental-health benefits and briefly discussed her divorces and her son Jack; her representative did not comment on when she began abstaining.

Reading Rainbow Host Mychal Threets to Seek Hospital Help Amid Mental Health Struggles
entertainment6 days ago

Reading Rainbow Host Mychal Threets to Seek Hospital Help Amid Mental Health Struggles

Mychal Threets, host of the Reading Rainbow reboot, announced on Threads that he will check himself into the hospital, writing that he is not okay and may never be okay, and that he is seeking help while noting he is currently safe. The 36-year-old has long spoken about battles with depression and anxiety, and has discussed mental health in interviews as he built his library-themed persona and led the YouTube revival of Reading Rainbow; fans and colleagues publicly offered support.

Acupuncture May Rewire Depression Brain Circuits, New Imaging Sheds Light
science7 days ago

Acupuncture May Rewire Depression Brain Circuits, New Imaging Sheds Light

A meta-analysis of seven trials (357 adults with major depressive disorder) finds acupuncture produces distinct neuroplastic changes in emotion and reward circuits, differing from antidepressants by activating the right cingulum and caudate and, with more sessions, changes in the left amygdala. Acupuncture also showed greater reductions in depression and anxiety scores than antidepressants, though many participants were also on meds. The study suggests acupuncture could offer complementary mechanisms for treatment-resistant depression, but larger, longer-term, standardized trials and studies of underlying molecular pathways are needed.

Depression Tied to Shrinkage in a Key Memory Hub in the Brain
science10 days ago

Depression Tied to Shrinkage in a Key Memory Hub in the Brain

A USC-led study using MRI and PET scans of over 2,000 cognitively normal adults found that depression is linked to a smaller CA23DG portion of the hippocampus (comprising CA2/CA3 and the dentate gyrus), an association that largely held even after accounting for Alzheimer's risk factors. Antidepressant use and longer duration of depression were also associated with greater volume reductions in related hippocampal subregions, though the findings are correlational and do not establish causation or warrant changing treatment. Further longitudinal research is needed to understand the mechanisms at play.

Jennifer Esposito reveals celiac diagnosis after years of misdiagnosis and a psych ward stay
entertainment14 days ago

Jennifer Esposito reveals celiac diagnosis after years of misdiagnosis and a psych ward stay

Actress Jennifer Esposito recounts years of debilitating, misdiagnosed symptoms and severe depression that culminated in a psychiatric ward stay before doctors diagnosed her with celiac disease; after adopting a gluten-free diet and pursuing gut-health recovery, she’s now healthier, no longer has panic attacks, and hopes to help others facing similar health battles.

health16 days ago

Regular Daily Routines Linked to Less Pain and Depression in Older Adults

A University of Missouri study found that older adults who kept a consistent daily schedule—waking, first social interaction, main daytime activity, dinner, and bedtime within 45 minutes of their usual times—reported less physical pain, fewer depressive symptoms, and a lower BMI, regardless of insomnia status, suggesting that regular time cues help synchronize the body clock and support health, with social jet lag identified as a disruptor.

Herbal boost: Basil extract eases depression and anxiety when added to antidepressants
mental-health17 days ago

Herbal boost: Basil extract eases depression and anxiety when added to antidepressants

In a randomized, single-blind trial, 60 adults with major depressive disorder and concurrent anxiety received sertraline plus either 1100 mg of dried basil leaf extract nightly or a placebo for four weeks. The basil group showed greater symptom reductions on both the Beck Depression Inventory and the Hamilton Anxiety Rating Scale, with depression dropping from about 39 to 21 and anxiety from about 33 to 13, compared with placebo reductions to roughly 30 and 25, respectively. Basil was well tolerated, but the study’s short duration and single-blind design mean longer-term effects and causality require further research; basil should be viewed as an add-on, not a replacement for standard care.

UK NHS trial shows promise of a single-dose psilocybin with therapy for hard-to-treat depression
health19 days ago

UK NHS trial shows promise of a single-dose psilocybin with therapy for hard-to-treat depression

A UK National Health Service–based phase 2 feasibility randomized trial tested a single 25‑mg dose of psilocybin with psychological support versus placebo in 60 adults with treatment‑resistant major depressive disorder. At three and six weeks, the psilocybin group showed large, clinically meaningful reductions on the MADRS compared with placebo (about a 10–13 point advantage) and higher response/remission rates, with improvements in anxiety and well‑being. Adverse events were mostly mild and not clearly linked to the drug, and blinding was imperfect, suggesting expectancy effects contributed to the outcome. Feasibility metrics (recruitment, retention, data completeness) were favorable, supporting larger efficacy trials and consideration of cost‑effectiveness in public healthcare. Overall, the study demonstrates the practicality of delivering psilocybin‑assisted therapy in NHS settings, while recognizing limitations that future trials should address.

Publicly funded trial finds psilocybin eases treatment-resistant depression
science19 days ago

Publicly funded trial finds psilocybin eases treatment-resistant depression

A publicly funded randomized trial found that a 25mg dose of psilocybin plus psychological support significantly boosted response (43% at 3 weeks, 56% at 6 weeks) and remission (40% at 3 weeks vs 3% placebo), with effects sustained through six weeks, suggesting psilocybin therapy could help treatment-resistant depression and warrants larger, publicly funded trials in community settings.