Adult Brains Form New Neurons Even at 78, Rewriting Neurogenesis Rules

A 2025 study from Karolinska Institutet provides direct evidence that the adult human hippocampus can generate new neurons, identifying dividing progenitor cells in the dentate gyrus of individuals up to age 78 using single-nucleus RNA sequencing. This supports ongoing adult neurogenesis in at least one brain region, though there is wide individual variation and it does not imply broad brain rejuvenation or immediate therapies; replication is needed to confirm findings and understand drivers of variability.