Brain resilience switch: CgA protein shields against Alzheimer's symptoms in mice
TL;DR Summary
UCSD researchers identify chromogranin A (CgA) as a key driver linking amyloid-beta/tau pathology to cognitive decline: mice lacking CgA still develop Alzheimer’s brain changes but remain cognitively sharp, revealing innate resilience mechanisms and a potential preventive target, though human confirmation and safety considerations are needed, and some authors have industry ties.
Topics:health#alzheimers-disease#asymptomatic-alzheimers#chromogranin-a#cognitive-resilience#mouse-model#science
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