High-Dose Psilocybin Sparks Temporary Functional Gains in Alzheimer's Case

TL;DR Summary
A Brazilian case study reports that an elderly woman with advanced Alzheimer's briefly regained bladder control and speech after a single very high psilocybin dose (5g), with further improvements after a second 3g dose a month later; researchers note the results are observational and not a cure, suggesting transient access to latent functional capacities under psychedelic neuromodulation and calling for controlled trials as psilocybin is explored for cognitive decline and mood disorders elsewhere.
- Huge Psilocybin Dose Has Incredible Effect on Elderly Dementia Patient ScienceAlert
- Alzheimer’s patient gets back speech, bladder control and memory in groundbreaking drug trial New York Post
- Psilocybin Mushroom Case Report Documents Transient Functional Recovery in Advanced Alzheimer's Disease MycoStories
- Alzheimer's Patient Shows Miraculous Improvement After Taking Experimental Drug Wide Open Country
- The natural compound that temporarily reverses advanced dementia symptoms The Independent
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