High-Dose Psilocybin Sparks Temporary Functional Gains in Alzheimer's Case

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Source: ScienceAlert
High-Dose Psilocybin Sparks Temporary Functional Gains in Alzheimer's Case
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TL;DR Summary

A Brazilian case study reports that an elderly woman with advanced Alzheimer's briefly regained bladder control and speech after a single very high psilocybin dose (5g), with further improvements after a second 3g dose a month later; researchers note the results are observational and not a cure, suggesting transient access to latent functional capacities under psychedelic neuromodulation and calling for controlled trials as psilocybin is explored for cognitive decline and mood disorders elsewhere.

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