Omega-3 and Low-Dose Aspirin Match Antibiotics for Severe Gum Disease in Year-Long Trial

A yearlong Brazilian study of 109 people with advanced periodontitis found that daily omega-3 with low-dose aspirin achieved nearly the same clinical benefits as the antibiotics regimen (metronidazole + amoxicillin) in reducing deep gum pockets. A placebo/standard care group performed much worse, while adding antibiotics to omega-3 and aspirin did not improve outcomes beyond either treatment alone. Benefits persisted for months after treatment, suggesting a potential antibiotic-sparing option pending more evidence.