Tag

Antibiotic Resistance

All articles tagged with #antibiotic resistance

environment2 days ago•36 min saved

Glyphosate may fuel drug-resistant bugs spreading from farms to clinics

Argentine researchers found bacteria from a wetlands site never sprayed with glyphosate still developed tolerance to the weedkiller, and hospital drug-resistant strains survived high doses of glyphosate in tests. Genetic analysis linked the wetlands bacteria to hospital pathogens, suggesting glyphosate exposure and runoff could help spread resistance genes between farms and clinics, raising regulators’ and wastewater managers’ attention to pesticide testing for antibiotic-resistance side effects.

via Earth.com|

#antibiotic-resistance #drug-resistant-bacteria #environment

health6 days ago•4 min saved

Cruise hantavirus case prompts Canadian response, ACIP charter withdrawal, PACCARB to reconvene

The Public Health Agency of Canada confirmed an Andes strain hantavirus infection in a Canadian traveler aboard the MV Hondius, with a traveling partner testing negative and no additional cases identified. In the U.S., a passenger in Nebraska remains in isolation with negative test results and is reportedly denied home quarantine. Separately, HHS withdrew the ACIP charter renewal due to an administrative error amid Secretary Kennedy's efforts to reshape the panel. The Presidential Advisory Council on Combating Antibiotic-Resistant Bacteria (PACCARB) will reconvene on June 16 to help inform the next five-year national action plan for antibiotic resistance.

via cidrap.umn.edu|

#acip #antibiotic-resistance #cruise-ship

science11 days ago•3 min saved

Glyphosate May Drive Antibiotic-Resistant Bacteria Across Hospitals and Farmlands

New research finds that the widely used weedkiller glyphosate may select for antibiotic-resistant bacteria, with hospital strains showing high resistance to antibiotics and glyphosate alike. The study compared hospital, agricultural, and environmental strains and suggests resistance can spread between clinics and fields via environmental pathways, potentially amplifying antimicrobial resistance beyond antibiotics alone.

via SciTechDaily|

#amr #antibiotic-resistance #environmental-microbiology

science19 days ago•5 min saved

Common antihypertensive drug shows potential to kill MRSA by membrane disruption

A widely used blood pressure medication, candesartan cilexetil, demonstrated in lab and animal studies the ability to kill MRSA by disrupting its cell membrane; when combined with existing antibiotics it enhances effectiveness, with plans to move toward human trials.

via ScienceAlert|

#antibiotic-resistance #candesartan-cilexetil #drug-repurposing

health28 days ago•15 min saved

Nationwide Salmonella Outbreak Linked to Backyard Chickens Prompts CDC Alert

CDC reports 34 illnesses in 13 states (13 hospitalizations, no deaths yet) linked to backyard chickens. The Salmonella strains are resistant to multiple antibiotics, including fosfomycin, highlighting growing antibiotic resistance and prompting guidance on hygiene around poultry and avoiding kissing or snuggling birds.

via Gizmodo|

#antibiotic-resistance #backyard-chickens #health

science29 days ago•6 min saved

Graphene oxide: selective bacteria killer that spares human cells

KAIST researchers reveal that graphene oxide selectively disrupts bacterial membranes by binding to a molecule (POPG) present in bacteria but not human cells, killing a broad range of bacteria including drug-resistant strains while leaving human cells unharmed; when used as nanofibers, it stops bacterial growth and promotes faster wound healing, and its antibacterial properties endure after repeated washing, with real-world uses in antibacterial toothbrushes and textiles.

via Science Daily|

#antibacterial #antibiotic-resistance #graphene-oxide

science1 month ago•4 min saved

Bogland tormentil: a wildflower unlocking new ways to fight resistant bacteria

Lab tests show tormentil root extracts from bogland inhibit growth of antibiotic‑resistant bacteria, reduce biofilm formation, and boost the effectiveness of the antibiotic colistin at low doses. The active compounds ellagic acid and agrimoniin appear to work by iron chelation, starving bacteria of a key nutrient and hindering growth, pointing to a potential plant‑derived route to new antimicrobials and combination therapies.

via SciTechDaily|

#antibiotic-resistance #antimicrobial #biofilms

plants1 month ago•20 min saved

Tormentil wildflower offers new angle against antibiotic-resistant superbugs

A Southampton-led study finds tormentil, a small yellow bogland wildflower, slows the growth of the drug-resistant bacterium Acinetobacter baumannii and may boost the effectiveness of the last-resort antibiotic colistin. The researchers identified two active compounds, agrimoniin and ellagic acid, that starve bacteria of iron, with consistent antimicrobial activity across three Irish bogs, suggesting potential for plant-based drug development—though translating these findings into safe, effective medicines will require extensive further work.

via Earth.com|

#acinetobacter-baumannii #antibiotic-resistance #antimicrobial-compounds

health-and-medicine1 month ago•5 min saved

From skincare staple to potential antibiotic: madecassic acid fights drug-resistant bacteria

University of Kent researchers (with UCL) found madecassic acid, a Centella asiatica–derived compound used in skincare, can halt growth of antibiotic‑resistant E. coli by targeting the bacterial cytochrome bd complex; modified versions showed stronger effects, hinting at a new antimicrobial path and potential skincare microbiome implications.

via ScienceDaily|

#antibiotic-resistance #centella-asiatica #cytochrome-bd-complex

animals1 month ago•16 min saved

Wildlife as vectors for antibiotic‑resistant bacteria across ecosystems

A study of wildlife in northern Italy finds foxes and several bird species carry hospital-linked Klebsiella pneumoniae strains that resist multiple antibiotics, including the NDM-5 gene, signaling that antibiotic resistance is present beyond clinical settings. Researchers say wildlife can act as sentinels for environmental contamination and help map how resistance travels through ecosystems, aided by factors like wastewater and waste runoff. The findings show a low prevalence (about 2%) but indicate environmental reservoirs of high‑risk clones (like ST307) and shared plasmids, highlighting the need for broader wildlife monitoring and cleaner wastewater to slow the spread.

via Earth.com|

#animals #antibiotic-resistance #environmental-contamination

health1 month ago•14 min saved

CDC Warning: Drug-Resistant Shigella Poses New Public Health Threat

The CDC warns about XDR shigella, a drug-resistant Shigella strain causing shigellosis in the US, with infections up 8.5% from 2011 to 2023 and about 450,000 cases annually; the strain is resistant to most common antibiotics, leaving few oral treatments and sometimes requiring hospitalization for IV antibiotics; antimicrobial-resistant infections cost roughly $93 million in direct medical costs. Transmission is fecal-oral, via contaminated food/water and, increasingly, sexual activity; prevention centers on handwashing, safe food and water, and abstaining from sex during/after illness. Most infections resolve in 5–7 days, but young children, the elderly, and immunocompromised individuals remain higher risk.

via Hartford Courant|

#antibiotic-resistance #cdc #health

health1 month ago•2 min saved

U.S. Faces Growing Threat from Drug-Resistant Shigella, CDC Warns

CDC warns of a rise in extensively drug-resistant Shigella infections in the United States—from 0% resistance in 2011 to 8.5% in 2023—with about a third of patients hospitalized; Shigella spreads easily via contaminated water, food, surfaces, or person-to-person contact and causes shigellosis with diarrhea (often bloody), fever, and stomach pain 1–2 days after exposure, lasting about a week. Most mild cases improve with fluids and rest, but serious cases may require antibiotics, though there is not an approved treatment for shigellosis in the U.S. Populations at higher risk include children under 5, travelers, men who have sex with men, and people experiencing homelessness.

via LiveNOW from FOX|

#antibiotic-resistance #diarrhea #health

science1 month ago•9 min saved

Dry soil could accelerate antibiotic resistance, study says

New research suggests drought-stressed soil speeds up the natural processes that create and spread antibiotic resistance, as bacteria in dry, crowded pockets produce more antibiotics and exchange resistance genes. While some studies find correlations between arid regions and higher hospital infections, causation isn’t proven and other factors like tracking and healthcare access play a role. The findings emphasize the environment’s role in antibiotic resistance and the One Health perspective, linking climate-driven ecological change to human health and urging closer environmental monitoring alongside medical stewardship.

via The Conversation|

#antibiotic-resistance #drought #horizontal-gene-transfer

health1 month ago•55 min saved

CDC warns rising drug-resistant Shigella strains threaten US public health

The CDC warns that a new extensively drug‑resistant Shigella strain is spreading in the US, behind about 8.5% of Shigella infections in 2023 and continuing to rise. Hospitalization occurs in roughly a third of cases, though no deaths have been reported yet. Overall, drug‑resistant infections are a major US burden, with about 2.8 million cases and about 35,000 deaths annually, fueled by widespread antibiotic use in humans and animals and the spread of resistant strains.

via Daily Mail|

#antibiotic-resistance #cdc #health

health1 month ago•70 min saved

Airborne antiseptic-tolerant germs detected in ICUs, study hints

A Northwestern-led study finds trace chlorhexidine lingering in ICU rooms can promote antiseptic-tolerant bacteria. In 219 surface samples from six ICUs, about 36% showed tolerance, with sinks highlighted as hotspots and the possibility that aerosols can spread tolerant bacteria to nearby surfaces. Some tolerant strains carry plasmids that could also spread antibiotic resistance, though chlorhexidine remains effective at standard cleaning concentrations. The findings underscore the need for antimicrobial stewardship and more research into how antiseptic use may influence resistance beyond antibiotics.

via Live Science|

#antibiotic-resistance #antiseptic #bacteria