Two-Stage Gut Signal Triggers Appetite Loss During Infection
TL;DR
UC San Francisco researchers reveal a two-stage gut signaling pathway: parasite detection by tuft cells releases acetylcholine, which prompts enterochromaffin cells to release serotonin and activate vagal brain signals, leading to delayed appetite suppression as infection takes hold; the finding links gut immune response to behavior and could inform gut disorders like IBS and food intolerances.
Topics:healthscience#acetylcholine#appetite-loss#gut-brain-axis#parasitic-infection#science#tuft-cells
- Scientists discover why your appetite suddenly disappears when you’re sick ScienceDaily
- Parasites trigger epithelial cell crosstalk to drive gut–brain signalling nature.com
- New Research Explains How the Gut Detects Parasites and Triggers Sickness Response | Newswise Newswise
- Research explains why stomach bugs cause a lingering loss of appetite News-Medical
- Scientists Just Found Why You Suddenly Lose Your Appetite When Sick SciTechDaily
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