Omega-3 and Low-Dose Aspirin Match Antibiotics for Severe Gum Disease

A 1-year, multicenter trial with 109 patients having advanced periodontitis found that adding omega-3 and low-dose aspirin to standard subgingival therapy produced outcomes nearly identical to those achieved with a standard antibiotic regimen. The benefits persisted six months after stopping treatment, suggesting a lasting modulation of the inflammatory response. While promising as an antibiotic-sparing option for select patients, researchers caution that more evidence is needed before replacing antibiotics in routine dental care.