Self-organizing laser beam enables ultrafast, high-res brain imaging

MIT researchers reveal a laser that self-organizes into a stable pencil beam inside a multimode fiber under precise on-axis high-power conditions, enabling ultrafast, high-resolution 3D imaging of the blood–brain barrier and real-time tracking of drug uptake without fluorescent tags—potentially speeding brain-targeted therapy research by about 25x and opening paths to imaging neurons and other tissues.