Tag

Amyloid Protein

All articles tagged with #amyloid protein

Midlife Vitamin D Levels Tied to Lower Dementia Risk, Study Shows
wellness58 minutes ago

Midlife Vitamin D Levels Tied to Lower Dementia Risk, Study Shows

A Neurology study of 793 adults in their 30s–40s followed for 16 years found higher vitamin D in midlife associated with lower brain tau protein, a dementia-related marker, though amyloid levels weren’t affected and causality isn’t proven. With roughly 60% worldwide deficiency, researchers advise correcting vitamin D deficits and adopting brain-healthy habits—diet (fatty fish), regular physical activity, social and cognitive engagement, and managing vascular risks like diabetes, high blood pressure, and cholesterol—to support cognitive health later in life.

"Leqembi: A Promising Drug for Slowing Alzheimer's Progression, but Not a Cure"
health2 years ago

"Leqembi: A Promising Drug for Slowing Alzheimer's Progression, but Not a Cure"

The U.S. FDA has granted traditional approval for Leqembi (lecanemab), a new drug for the treatment of early Alzheimer's disease. Leqembi is a monoclonal antibody that slows the progression of symptoms by targeting the amyloid protein found in the brains of Alzheimer's patients. However, the drug is only indicated for individuals with proven amyloid protein in the brain and early Alzheimer's or mild cognitive impairment. It has shown some success in reducing amyloid protein deposition but has only modestly slowed the progression of the disease. Screening for Alzheimer's with this drug is not a high priority, and other lifestyle interventions such as diet, exercise, and cognitive training may be more beneficial in reducing dementia risk.

Sleep Problems Linked to Reduced Brain Volume and Alzheimer's Risk, Studies Find
health2 years ago

Sleep Problems Linked to Reduced Brain Volume and Alzheimer's Risk, Studies Find

Chronic sleep disturbances are an inescapable risk factor for Alzheimer's disease, according to scientists at Washington University School of Medicine in St. Louis, Missouri. The team demonstrated in a series of experiments that sleep deprivation prevents immune cells known as microglia from properly cleaning up deposits of amyloid protein during the sleep cycle, a finding that helps explain the long-observed connection between sleep loss and neurodegeneration. Amyloid proteins are the building blocks of gooey amyloid plaques, a key hallmark of Alzheimer's disease.