Tag

Androgen Deprivation Therapy

All articles tagged with #androgen deprivation therapy

health1 month ago•6 min saved

Structured lifestyle program improves quality of life for men on prostate cancer therapy

A UK randomized trial of 700 men on androgen deprivation therapy for prostate cancer found that the STAMINA program—supervised exercise, dietary guidance, and behavioral support—reduced deterioration in cancer-specific quality of life by up to one-third and lessened fatigue; the regimen was cost-effective and feasible within NHS trusts, with high attendance, and prompted Nuffield Health to plan broader rollout, including expansion to other cancers by 2030, though long-term survival effects remain unknown.

via Healthline|

#androgen-deprivation-therapy #exercise #health

medical-research2 months ago•8 min saved

Ultra-low PSA target linked to better survival in metastatic prostate cancer

A real-world Veterans Health Administration study of 4,890 men with metastatic hormone-sensitive prostate cancer found that achieving a PSA below 0.2 ng/mL within 9 months of starting testosterone-deprivation therapy was associated with a 54% lower risk of death over a median follow-up of about 2 years. Notably, patients who only achieved a 90% PSA decline without hitting the 0.2 ng/mL threshold did not see a survival benefit. The findings suggest targeting PSA <0.2 ng/mL as a key treatment-success metric and indicate that more aggressive therapy may be warranted for those who do not reach this level; adding another drug to further block testosterone improved odds of reaching the threshold.

via News-Medical|

#androgen-deprivation-therapy #medical-research #metastatic