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Anti Ige

All articles tagged with #anti ige

business15 days ago•5 min saved

Novartis to acquire Excellergy to accelerate next-gen anti-IgE therapy

Novartis will acquire Excellergy for up to USD 2 billion in upfront and milestone payments to bolster its immunology portfolio with Exl-111, a Phase 1, half-life–extended anti-IgE antibody designed to dissociate receptor-bound IgE and drive faster, deeper IgE signaling suppression. If approved, Exl-111 could improve symptom control and dosing convenience across IgE‑driven diseases such as food allergy, chronic urticaria, inducible urticaria and asthma; closing is targeted for H2 2026, subject to regulatory approvals.

via Novartis|

#allergy #anti-ige #business

business2 months ago•9 min saved

GSK to acquire RAPT Therapeutics, adding long-acting anti-IgE for food allergies

GSK has agreed to buy RAPT Therapeutics for $58 per share (~$2.2 billion equity, ~$1.9 billion net) to gain ozureprubart, a long-acting anti-IgE antibody in phase IIb aimed at prophylactic protection against food allergies. The therapy could allow dosing every 12 weeks (vs current injections every 2–4 weeks), addressing a major unmet need and expanding GSK’s allergy portfolio. The deal is structured as a tender offer with closing expected in Q1 2026, and includes milestone/royalty arrangements linked to RAPT’s partner.

via GSK|

#anti-ige #business #food-allergies