Tag

Antiretroviral

All articles tagged with #antiretroviral

health1 month ago•7 min saved

VH-499 shows early promise as a new HIV-1 capsid inhibitor

Phase 2a results for VH-499 (VH4011499), a HIV-1 capsid inhibitor, show dose-dependent viral-load reductions in 23 ART-naive adults by day 11 with good tolerability and no significant CYP3A4 interference; all participants started standard ART on day 11. While encouraging, phase 3 trials are needed to establish efficacy and safety against existing therapies. The study was funded by ViiV Healthcare and published in Clinical Infectious Diseases.

via ScienceAlert|

#antiretroviral #capsid-inhibitor #clinical-trial

health1 year ago•3 min saved

Global HIV Cases and Deaths Plummet to Historic Lows

The United Nations reports that HIV cases in 2023 reached their lowest since the 1980s, with 1.3 million new infections, but warns that progress is too slow to meet the goal of ending AIDS by 2030. Antiretroviral treatments have contributed to the decline, yet 9.3 million people with HIV are not receiving treatment. Despite global progress, 28 countries saw increased infections, and access to preventative treatments like PrEP remains limited. A new drug, lenacapavir, shows promise but is costly, raising concerns about accessibility.

via ScienceAlert|

#antiretroviral #health #hiv

health1 year ago•3 min saved

Global HIV Cases and Deaths See Significant Decline

Global progress in reducing HIV infections and deaths is evident, with new cases and fatalities at their lowest since the 1980s and 2004, respectively. However, challenges remain, as 1.3 million new cases in 2023 exceed targets for ending AIDS by 2030. While treatments like PrEP and antiretrovirals are effective, access is limited, especially in poorer regions. A promising new drug, lenacapavir, offers hope with its biannual injection, but cost and access issues persist. Despite advancements, a vaccine for HIV remains elusive.

via Geo News|

#antiretroviral #health #hiv