Tag

B Cell Lymphoma

All articles tagged with #b cell lymphoma

Off-the-shelf CAR-T shows potential to delay lymphoma relapse in interim Phase 3 results
biotech1 month ago

Off-the-shelf CAR-T shows potential to delay lymphoma relapse in interim Phase 3 results

Allogene Therapeutics reported interim Phase 3 data for its off-the-shelf CAR-T therapy cema-cel in B-cell lymphoma, showing 58% MRD negativity in treated patients versus 16% in those observed with standard care, a result that could delay or prevent cancer relapse in high-risk patients, though the data are preliminary.

"Stanford Scientists Develop Cancer-Killing Drug by Flipping Cancer Driver"
health2 years ago

"Stanford Scientists Develop Cancer-Killing Drug by Flipping Cancer Driver"

Stanford researchers have developed a new drug that can transform a protein that typically promotes the growth of B cell lymphoma into a protein that causes cancer cells to die. By changing how an important B cell control gene is regulated, the drug acts as a chemical harness, pulling in another protein that alters the first protein's effect on gene expression.