
Vitamin B12: High Blood Levels Linked to Worse Cancer Outcomes, But Causality Remains Unclear
Elevated blood B12 is linked to poorer survival and more advanced disease in cancers (notably colon cancer), but researchers caution the association is likely not causal; tumors can disrupt B12 storage/transport and drive higher levels, while high dietary intake shows a U‑shaped link with cancer risk. Overall evidence is inconsistent, suggesting B12 may be a disease biomarker rather than a driver.
