David Botstein, Architect of Gene Mapping, Dies at 83
David Botstein, a pioneering molecular biologist who developed a gene-mapping approach using DNA marker variations and helped enable the human-genome project, died at 83 from Parkinson’s disease. His work bridged genetics and sequencing, guiding discoveries of disease genes and advancing interdisciplinary science education during stints at MIT, Genentech, Stanford, Princeton, and Calico.