All articles tagged with #car t cell
A CAR-T cell therapy that reprograms the immune system has put lupus into remission in early UK trials, with five of the first six patients in remission for more than 18 months and one showing improvement but a flare at 11 months. The approach destroys rogue B cells by using modified T cells and could extend to other autoimmune diseases, though long-term durability and broader efficacy remain to be seen.
Immunotherapy is maturing from research into real-life cancer care, with trials like dostarlimab showing tumor eradication without surgery in some patients. Researchers are expanding strategies—checkpoint inhibitors, CAR T-cell therapies, cancer vaccines, and treatment combinations—to boost response rates. While benefits can be life-changing, side effects exist and only a minority of tumors currently fit the best-immunotherapy profile, prompting a push toward personalized, multi-pronged approaches to help more patients.
A new cancer-inspired treatment called CAR T-cell therapy shows promise in effectively treating severe lupus, offering hope to patients who have exhausted conventional options, as demonstrated by Jennifer Le's successful case in Boston.