Unraveling Cancer Cell Pathways: CRISPR Screens Reveal γδ T Cell Detection Triggers
CRISPR screens have been used to decode the pathways in cancer cells that trigger the detection of γδ T cells, a type of immune cell. The study identified genes involved in the recognition of cancer cells by γδ T cells, shedding light on the mechanisms underlying their anti-tumor activity. The findings could potentially contribute to the development of new cancer immunotherapies.