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Channelrhodopsin

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2026 Nobel Prize Awards Optogenetics Pioneers for Light-Based Brain Control
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2026 Nobel Prize Awards Optogenetics Pioneers for Light-Based Brain Control

Karl Deisseroth, Peter Hegemann, and Georg Nagel won the 2026 Nobel Prize in Physiology or Medicine for developing optogenetics, a technique that uses light to control specific brain cells. The method relies on channelrhodopsin, a light-sensitive protein originally found in the alga Chlamydomonas. By inserting this protein into neurons, researchers can activate or inhibit cells with precision, enabling the mapping of neural circuits and the potential treatment of conditions like blindness, Parkinson’s disease, and epilepsy.