Tag

Cochrane

All articles tagged with #cochrane

Cochrane retracts invited AI-methods paper over COI disclosure breach
publishing-ethics-science-policy1 month ago

Cochrane retracts invited AI-methods paper over COI disclosure breach

Cochrane Evidence Synthesis and Methods invited Nested Knowledge to publish a paper detailing the AutoLit AI tool for evidence synthesis; the article appeared after an January invitation and was published in October, but a June 1 retraction cited a breach of Cochrane’s conflict-of-interest policy because authors disclosed equity in the platform and initially lacked a COI statement. Editorial oversight was acknowledged as a factor. The authors say the invitation and acceptance were in good faith and that they plan to submit the manuscript to a venue not bound by Cochrane’s COI policies. Retractions over COI disclosures are uncommon, but the case underscores how conflicts of interest can trigger withdrawals even for methodological/AI-focused papers.

Cochrane review questions real-world benefits of anti-amyloid Alzheimer's drugs
health3 months ago

Cochrane review questions real-world benefits of anti-amyloid Alzheimer's drugs

A new Cochrane analysis of 17 trials (over 20,000 participants) finds amyloid-beta–targeting monoclonal antibodies, including Leqembi and Kisunla, likely confer little to no meaningful cognitive or functional benefit in mild cognitive impairment or mild Alzheimer's, while modestly increasing the risk of ARIA-E (brain swelling); despite some trial-specific benefits for individual drugs, the overall class effect is in doubt, prompting calls to pursue other disease mechanisms.