Tag

Coronaviruses

All articles tagged with #coronaviruses

science1 month ago•47 min saved

AI-Designed Vaccine Targets Coronavirus Family, Early Trial Shows Promise

Researchers at the University of Cambridge used AI to design a DNA-based vaccine targeting immutable components of the sarbecovirus family (which includes SARS and SARS-CoV-2). In a small first-in-human trial with 39 participants, the AI-designed vaccine activated antibodies and was well tolerated across doses, suggesting potential for a universal coronavirus vaccine, though the durability and magnitude of protection require further study.

via Yahoo|

#ai-designed-vaccine #cambridge #coronaviruses

science1 month ago•3 min saved

AI-Crafted Universal Coronavirus Vaccine Clears Phase I Trial

Researchers at Cambridge used AI to design a pan-coronavirus vaccine, pEVAC-PS, which in a Phase I trial in 39 healthy volunteers appeared safe and elicited cross-reactive immune responses to multiple sarbecoviruses; the team plans Phase II trials and has spun off DIOSynVax to commercialize the AI platform for universal vaccines against threats like flu and Ebola.

via Gizmodo|

#artificial-intelligence #coronaviruses #phase-i-trial

health1 year ago•3 min saved

Scientists Warn of Near-Identical Bat Viruses with Pandemic Potential

A study warns that a subgroup of bat viruses called HKU5, related to MERS-CoV, is just one mutation away from potentially infecting humans, highlighting the need for ongoing surveillance and research to prevent future pandemics.

via Times of India|

#coronaviruses #health #hku5

health3 years ago•2 min saved

New coronaviruses discovered in UK bats with potential to infect humans

A survey of UK bat species has uncovered new coronaviruses, including some from the same group as SARS-CoV-2. Laboratory studies suggest that some share key adaptations with SARS-CoV-2 but are unlikely to spread in humans without further evolution. The researchers created pseudoviruses to gauge the threat posed by the UK coronaviruses and found that one sarbecovirus found in a lesser horseshoe bat had a spike protein that was able to infect human cells by attaching to a protein called ACE2, the same receptor used by SARS-CoV-2. However, the UK sarbecovirus's version of spike didn't attach nearly as strongly as SARS-CoV-2's, making it unlikely that the virus could readily infect people and spread.

via Nature.com|

#bats #coronaviruses #health