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Cytomegalovirus

All articles tagged with #cytomegalovirus

Dormant viruses wake up in COVID-19 patients, impacting severity and long COVID
health1 month ago

Dormant viruses wake up in COVID-19 patients, impacting severity and long COVID

A year-long study of over 1,150 hospitalized, unvaccinated COVID-19 patients found that about 48% experienced reactivation of dormant viruses, notably Epstein-Barr virus and cytomegalovirus, with reactivations linked to greater acute severity and higher 1-year mortality in the critically ill; reactivation of Anelloviridae during recovery was associated with long COVID fatigue and disability. The study does not prove causation and has limitations (older SARS-CoV-2 strains, no vaccination status, sampling constraints), but suggests viral reactivation could influence COVID-19 outcomes and may inform risk assessment and future therapies pending further research.

Severe COVID-19 May Unleash Dormant Viruses, Study Finds
science1 month ago

Severe COVID-19 May Unleash Dormant Viruses, Study Finds

A multi-center study of 1,154 hospitalized COVID-19 patients over a year found reactivation of 11 dormant viruses within the first 40 days of admission, including Epstein-Barr virus, cytomegalovirus, herpes simplex virus-1, and Anelloviridae. Reactivation appeared linked to inflammation rather than immune suppression and was also associated with long-COVID and long-term disability in some cases, though causation was not established. The findings shed light on how severe COVID-19 can impact the body’s virome and may inform future diagnostics and treatments, especially for those with severe disease.