
Health Officials Push Back on Benadryl Challenge as Deadly Online Trend Persists
The Benadryl Challenge—a dangerous online trend encouraging high-dose diphenhydramine (Benadryl) use to induce hallucinations—has been linked to teen deaths since 2020, with a study suggesting as many as 131 U.S. deaths through 2024. In 2026 the trend continued, prompting public health efforts focused on early education, risk communication, medication safety, and cross‑sector action (FDA warnings, platform safeguards, school programs, caregivers, and poison control) to curb harm and prevent future outbreaks.











