Spacing GLP-1 Shots May Sustain Weight Loss
A small, nonrandomized chart review of 34 patients found that extending GLP-1 weight‑loss injections to every 10–14 days (and up to six weeks) helped most maintain weight loss and metabolic benefits over 36 weeks, with only four gaining weight and many staying near normal BMI. The study’s limitations include lack of a control group, nonrandomized design, and self-selected participants, which limits generalizability. About 12% later returned to weekly dosing after weight regain, suggesting individualized dosing could work for some, but more rigorous research is needed.