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Endo 2026

All articles tagged with #endo 2026

Menopause hormone therapy appears to guard against bone thinning in new study
health31 minutes ago

Menopause hormone therapy appears to guard against bone thinning in new study

A retrospective cohort study of 387 postmenopausal women presented at ENDO 2026 found those using menopausal hormone therapy had 69% lower odds of low bone mineral density than non-users (31.8% vs 56.2%), with higher lumbar spine and total hip T-scores, suggesting MHT may protect against osteoporosis. The study is observational and not peer‑reviewed, and regimens varied; risks such as uterine cancer, heart attack, stroke, and breast cancer should be weighed, with decisions individualized.

GLP-1 Weight-Loss Drugs Trim Pounds But Also Trim Activity
health-and-medicine3 hours ago

GLP-1 Weight-Loss Drugs Trim Pounds But Also Trim Activity

A study presented at ENDO 2026 analyzed Fitbit data from NIH All of Us and found that adults with obesity who started GLP-1 medications (semaglutide or tirzepatide) lost weight but became less physically active. Average daily steps dropped from 5,047 to 4,487 and moderate-to-vigorous physical activity fell from 28 to 22 minutes per day, with the largest decreases in men and those reporting joint/muscle pain. Age, heart failure, and prior stroke did not change the trend. The researchers stress that exercise should accompany GLP-1 therapy to protect muscle and long-term health, marking the first large wearable-data study of activity in users of these drugs.