Tag

Endo 2026

All articles tagged with #endo 2026

Menopause Hormone Therapy Cuts Bone-Weakening Risk by 69%
health1 month ago

Menopause Hormone Therapy Cuts Bone-Weakening Risk by 69%

New data presented at ENDO 2026 show postmenopausal women using hormonal therapy have about a 69% lower risk of low bone mineral density in the spine and hip than nonusers, with findings holding after adjusting for age, menopause duration, vitamin D, smoking and other factors. While HRT can ease symptoms and reduce fractures, clinicians still weigh cancer risks and typical usage limits (seven years for estrogen alone, three to five years for estrogen-progestin).

Menopause hormone therapy appears to guard against bone thinning in new study
health2 months ago

Menopause hormone therapy appears to guard against bone thinning in new study

A retrospective cohort study of 387 postmenopausal women presented at ENDO 2026 found those using menopausal hormone therapy had 69% lower odds of low bone mineral density than non-users (31.8% vs 56.2%), with higher lumbar spine and total hip T-scores, suggesting MHT may protect against osteoporosis. The study is observational and not peer‑reviewed, and regimens varied; risks such as uterine cancer, heart attack, stroke, and breast cancer should be weighed, with decisions individualized.

GLP-1 Weight-Loss Drugs Trim Pounds But Also Trim Activity
health-and-medicine2 months ago

GLP-1 Weight-Loss Drugs Trim Pounds But Also Trim Activity

A study presented at ENDO 2026 analyzed Fitbit data from NIH All of Us and found that adults with obesity who started GLP-1 medications (semaglutide or tirzepatide) lost weight but became less physically active. Average daily steps dropped from 5,047 to 4,487 and moderate-to-vigorous physical activity fell from 28 to 22 minutes per day, with the largest decreases in men and those reporting joint/muscle pain. Age, heart failure, and prior stroke did not change the trend. The researchers stress that exercise should accompany GLP-1 therapy to protect muscle and long-term health, marking the first large wearable-data study of activity in users of these drugs.