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Gene Regulatory Networks

All articles tagged with #gene regulatory networks

science2 hours ago•31 min saved

Stimulation reshapes gene-linked neural assemblies in the human brain

A study using an ex vivo platform combines microelectrode array stimulation with recording and single-nucleus RNA sequencing on resected human temporal cortex, showing that stimulation strengthens cell assemblies and links these changes to cell-type–specific gene regulatory networks; they also identify common gene-expression signatures after in vivo stimulation, suggesting targets for neuromodulation therapies and providing a foundation for genetics-guided brain stimulation. Data are available in GEO (GSE288939) with interactive datasets for exploration.

via Nature|

#cell-assemblies #ex-vivo-brain-tissue #gene-regulatory-networks

science-and-technology2 years ago•3 min saved

Quantum Computing Unveils Gene Relationship Predictions

Researchers at Texas A&M University have demonstrated how quantum computing can be used to predict gene relationships and map gene regulatory networks (GRNs). By leveraging the capabilities of quantum computing, the team was able to identify previously unknown links between genes, providing a more comprehensive understanding of how genes influence each other. This breakthrough has significant implications for biomedical research, as it can help scientists predict gene expression and potentially control cellular processes, such as inhibiting the growth of cancer cells. While the field of quantum computing in biology is still in its early stages, this study highlights its potential for advancing genetic research and improving our understanding of complex biological systems.

via Phys.org|

#biomedical-science #gene-regulatory-networks #genetic-research