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Ischemia Reperfusion

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Arctic squirrels offer blueprint for slowing human metabolism in emergencies
science7 days ago

Arctic squirrels offer blueprint for slowing human metabolism in emergencies

Researchers studying Arctic ground squirrels, which can survive months of extreme cold by entering a deep, hibernation-like state, aim to translate this ability into human therapies that slow metabolism to buy time during heart attacks, strokes, and brain injuries. Approaches include triggering hibernation-like metabolic slowdown via adenosine-like signals or targeted brain circuit manipulation, with potential benefits for organ preservation and even long-term spaceflight, though translating these findings to humans remains experimental and challenging.