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Jama

All articles tagged with #jama

Guideline Shift Expands Statin Eligibility to 87.5 Million Americans
health12 days ago

Guideline Shift Expands Statin Eligibility to 87.5 Million Americans

A JAMA analysis of the 2026 ACC/AHA cholesterol guidelines shows 21.5 million more U.S. adults now qualify for statins, bringing the total to about 87.5 million. The expansion focuses on long-term lifetime risk rather than just 10-year risk, with older adults and people with risk factors more likely to qualify. Whether to start a statin should be individualized, possibly aided by tests like coronary calcium scoring, alongside lifestyle changes; statins are generally safe with mostly minor side effects.

Antihistamine Nasal Spray May Lower COVID Risk, New Study Finds
health3 months ago

Antihistamine Nasal Spray May Lower COVID Risk, New Study Finds

A phase 2 JAMA trial with 450 vaccinated adults in Germany found that using azelastine nasal spray (3–5 times daily for ~56 days) reduced COVID-19 infection risk to 2.2% vs 6.7% for placebo, shortened illness duration (3.4 vs 5.14 days), and lowered overall viral infections (8.4% vs 18.8%). Side effects were usually mild (e.g., bitter taste, nosebleeds, fatigue). Experts say it could be complementary to vaccines but not a substitute, and more research is needed before recommending it as a preventive measure.

"NIH Research: No Physical Evidence of Brain Injuries in Havana Syndrome Cases"
health-science2 years ago

"NIH Research: No Physical Evidence of Brain Injuries in Havana Syndrome Cases"

The National Institutes of Health conducted an investigation into the "Havana syndrome" and found no significant evidence of brain injuries in over 80 patients stationed in various locations. The studies, published in JAMA, aimed to assess the physical condition of the patients rather than determine the origin of the ailments. While the findings do not resolve the medical mystery, they suggest that the patients do not show evidence of brain damage and many are showing signs of improvement in their symptoms. The research has reignited the controversy surrounding the global medical mystery and raised doubts in the scientific and intelligence communities about the existence of unidentified adversaries targeting government officials with an exotic weapon.

The Science is Clear: Face Masks Effectively Protect Against COVID-19
health2 years ago

The Science is Clear: Face Masks Effectively Protect Against COVID-19

A new study published by the Journal of the American Medical Association (JAMA) confirms that masks provide protection against COVID-19. The study, which reviewed previous research, found robust evidence supporting the use of masks in reducing the spread of the virus. Despite the scientific consensus, the debate around masking persists, with some viewing it as a political rather than a scientific issue. The study emphasizes the importance of understanding the role of masks in preventing the spread of respiratory viruses, as future epidemics or pandemics are likely. The authors recommend a layered approach, including vaccination, isolation of infectious individuals, and the use of high-quality masks, to limit illness and death from COVID-19.