Tag

Cholesterol

All articles tagged with #cholesterol

health-and-science2 days ago•4 min saved

Gut Bacteria Identified as Natural Cholesterol Regulators in Heart Disease Research

A study published in Nature reveals that the common gut bacterium Bacteroides uniformis produces pentadecanoic acid, a molecule that reduces arterial plaque and cholesterol in mice by targeting the same enzyme as statin drugs. While human data shows a correlation between low levels of this molecule and heart disease, researchers emphasize that clinical applications remain distant. Concurrently, a separate Stanford study links Bifidobacterium abundance to recovery in chronic heart failure, suggesting broader microbiome roles in cardiac health.

via Nature|

#bacteroides-uniformis #cardiovascular-health #cholesterol

health4 days ago•425 min saved

Dietitian Names Beans as Top Plant Protein for Lowering Cholesterol

Registered dietitian Natalie Rizzo identifies beans as the premier plant-based protein for lowering LDL cholesterol due to their high soluble fiber content. Soluble fiber binds to cholesterol in the digestive tract, facilitating its removal from the body. Navy beans lead with over 9 grams of fiber per serving, followed by black and red adzuki beans at approximately 8 grams. Lentils and nuts are also recommended for their fiber and unsaturated fat profiles, which support heart health when replacing saturated fats.

via TODAY.com|

#cholesterol #dietitian #fiber

health4 days ago

New US Guidelines Expand Statin Eligibility to 87.5 Million Adults

The American Heart Association has updated its cholesterol guidelines, expanding the age range for cardiovascular risk assessment from 40-75 to 30-79. This change now qualifies approximately 87.5 million Americans, or more than half of adults in that age bracket, for potential statin treatment. The update includes a 21.5 million increase in eligible patients since the 2018 guidelines. While statins effectively lower 'bad' LDL cholesterol by 30-50%, experts emphasize that medication is not a substitute for lifestyle changes. The new framework aims to identify risk earlier, potentially preventing arterial plaque formation before it becomes irreversible, though long-term data on starting medication in one's 30s remains limited.

via The Telegraph|

#american-heart-association #cardiovascular-health #cholesterol

health5 days ago•9 min saved

Large Meta-Analysis Finds Statin Side Effects Far Less Severe Than Public Perception

A major meta-analysis in The Lancet suggests that while statins cause minor increases in muscle pain, liver enzyme changes, and diabetes risk, they do not significantly cause memory loss, depression, or sleep issues. Most reported muscle complaints are not actually caused by the drug, yet poor adherence remains a critical issue.

via Medscape|

#cardiovascular-health #cholesterol #clinical-trials

health-and-wellness5 days ago•18 min saved

New Data Pinpoints 60-100g Daily Whole Grain Intake as Optimal for Heart Health

A meta-analysis of 87 randomized trials involving over 6,500 adults reveals that consuming 60 to 100 grams of whole grains daily yields the greatest improvements in cardiovascular risk factors. This intake, equivalent to four to six servings, significantly lowers cholesterol, blood pressure, and body weight. The benefits are most pronounced when whole grains replace refined grains rather than simply being added to the diet.

via The Washington Post|

#blood-pressure #cardiovascular-health #cholesterol

health11 days ago•4 min saved

One-Shot CRISPR Therapy Sustains 52% Cholesterol Drop for One Year

A Phase 1 trial of CTX310, a CRISPR-based gene-editing therapy, demonstrated that a single infusion can reduce LDL cholesterol by 52.5% and triglycerides by 47.8% for at least one year. The treatment targets the ANGPTL3 gene in the liver, offering a potential permanent alternative to daily medications for patients with resistant lipid disorders. While early results are promising, larger trials are needed to confirm long-term safety and efficacy.

via Futura, le média qui explore le monde|

#cardiovascular #cholesterol #clinical-trials

health-and-medicine11 days ago•3 min saved

CRISPR Therapy Maintains 52% Cholesterol Reduction After One Year

A single infusion of the experimental CRISPR therapy CTX310 reduced LDL cholesterol by 52.5% and triglycerides by 47.8% in a 15-patient trial, with effects persisting for one year. The treatment targets the ANGPTL3 gene in the liver, offering a potential one-time alternative to daily medications for patients with resistant lipid disorders.

via sciencedaily.com|

#cardiovascular-disease #cholesterol #clinical-trials

health13 days ago•4 min saved

New Meta-Analysis Suggests 4 to 6 Daily Servings of Whole Grains Optimize Heart Health

A large meta-analysis published in the European Heart Journal indicates that consuming 60 to 100 grams of whole grains daily, equivalent to four to six servings, yields the greatest reductions in cardiovascular risk factors. This exceeds current US dietary guidelines, which recommend two to four servings. While benefits for weight and cholesterol are high-certainty, the study notes that long-term outcomes like heart attacks require further research.

via Fox News|

#cardiovascular-health #cholesterol #dietary-guidelines

More Whole Grains Linked to Broad Improvements in Heart and Metabolic Health

health24 days ago•2 min saved

Three daily servings of whole grains may bolster heart health, study shows

A meta-analysis in the European Heart Journal finds that a diet including whole grains is linked to small but meaningful improvements in cardiovascular risk markers; benefits start around 90 grams per day (about three servings) and increase with four to six servings, affecting cholesterol, blood pressure, weight, and waist circumference over time. Experts emphasize there is no universal daily target; instead, swap refined grains for whole grains and follow a broader heart‑healthy pattern—vegetables, fruits, and minimizing saturated fat, added sugar, salt, and ultraprocessed foods—while checking that packaged foods list whole grains as the first ingredient.

via CNN|

#cardiovascular-disease #cholesterol #health

science29 days ago•6 min saved

DNA therapy cuts PCSK9 and lowers cholesterol in mice, hinting at a statin-free option

Researchers used polypurine hairpins (PPRHs) to suppress PCSK9 gene expression, increasing LDL receptors. In human liver cells HpE12 reduced PCSK9 RNA by 74% and protein by 87%. In transgenic mice, a single HpE12 dose lowered plasma PCSK9 by 50% and cholesterol by 47% after three days, suggesting a potential statin-free approach that still needs safety testing in humans.

via Science Daily|

#cholesterol #dna-based-therapy #ldl-cholesterol

health1 month ago•56 min saved

Daily Avocado Habit Linked to Lower LDL, New Study Finds

A six-month Habitual Diet and Avocado Trial with 786 adults found that adding one avocado per day to the diet lowered LDL cholesterol by about 49 nmol/L and could translate to roughly a 4% lower risk of heart disease, a modest but meaningful improvement. Avocados provide monounsaturated fats, phytosterols, and fiber, which help explain the benefit, especially when replacing foods high in saturated fat. Experts say avocado is not a magic bullet and emphasize a broader heart-healthy lifestyle—plenty of vegetables, fruits, whole grains, regular exercise, and medications when prescribed. The study was funded by the Avocado Nutrition Center, but researchers say the sponsor did not influence the study design or interpretation.

via AOL.com|

#avocado #cholesterol #diet

health1 month ago•4 min saved

Five Burgers a Week Yield Surprising LDL Drop, Study Finds

A Nutrients study followed 23 men who ate five burgers per week for five weeks. Those who consumed high-fat beef (≈25% fat) showed reductions in LDL cholesterol and blood pressure and improved flow-mediated dilation (blood vessel function), while low-fat beef did not improve vessel function. Interestingly, both burger types lowered HDL (“good”) cholesterol, challenging the idea that saturated fat from red meat always harms heart health.

via New York Post|

#blood-pressure #burgers #cholesterol

health1 month ago•60 min saved

Eggs and Liver Health: A Hepatologist Explains the Nuanced View

A hepatologist notes that eggs sit in a gray area for liver health: they provide satiating protein and choline that can support the liver, but their cholesterol content means effects vary with overall diet and metabolic health. Studies on egg intake and MASLD/NAFLD conflict—some show higher risk with limited eggs, others show no association and suggest choline may be protective. For healthy individuals, 1–2 eggs daily can fit in a balanced diet, but those with high cholesterol may want to eat them less often. Emphasize liver-friendly breakfasts with whole foods (Greek yogurt or plant proteins, fiber-rich toast with avocado) and beverages like coffee/tea, while avoiding sugar-heavy pastries and fruit juice and limiting processed meats.

via AOL.com|

#breakfast #cholesterol #eggs

lifestyle1 month ago•12 min saved

Psyllium husk: separating hype from reality in ‘nature’s Ozempic’ claims

The piece explains psyllium husk as a high-fiber supplement that forms a gel when mixed with water and can aid digestion, cholesterol, and blood sugar; experts say it isn’t a magic fix like GLP-1 drugs, though some studies show LDL reductions and improved glucose control. The powder is recommended for gradual dosing (start around 3 g) with plenty of water (about 500 ml per 20 g of fiber) to avoid gut issues, and it can be added to smoothies or homemade jams. While it may help with certain conditions, it won’t guarantee weight loss, and people with Crohn’s disease or those on medications should consult a doctor due to absorption concerns. Price is affordable (about £4 for 100 g), and the overall message is to prioritize a varied, fiber-rich diet and use psyllium as a supplement rather than a cure-all.

via The Independent|

#cholesterol #gut-health #lifestyle