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Lenacapavir

All articles tagged with #lenacapavir

Gilead and Merck Report Promising Phase 3 Results for Weekly HIV Regimen Islatravir/Lenacapavir
health1 month ago

Gilead and Merck Report Promising Phase 3 Results for Weekly HIV Regimen Islatravir/Lenacapavir

Gilead and Merck announced topline Phase 3 results for the investigational once-weekly HIV regimen islatravir/lenacapavir (ISL/LEN) from ISLEND-1 and ISLEND-2, showing the Week 48 primary endpoint was met and non‑inferiority to Biktarvy or standard therapy with a comparable safety profile. The companies plan regulatory filings and full data presentations at a future congress, potentially introducing the first weekly oral HIV treatment if approved.

via Merck.com|
#health#hiv#islatravir
South Africa bets on biannual HIV prevention with $72M Lenacapavir rollout
health1 month ago

South Africa bets on biannual HIV prevention with $72M Lenacapavir rollout

South Africa announced a R1.3 billion ($72 million) rollout to deploy Lenacapavir, a long-acting HIV prevention injection given twice a year, across 360 clinics in 24 high-burden districts, aiming to reach about 1 million people by 2027 with support from the Global Fund and CIFF; the program seeks affordable generics via a voluntary license by 2027 and a broader push to manufacture 60% of Africa's medical products locally by 2040.

via Business Insider Africa|
#ciff#global-fund#health
Gilead's Lenacapavir Dilemma: A HIV Breakthrough Hindered by Access Rules
business3 months ago

Gilead's Lenacapavir Dilemma: A HIV Breakthrough Hindered by Access Rules

Lenacapavir could be a game-changer in HIV, but Gilead’s practice of not selling directly to Doctors Without Borders (MSF), limiting supply via the Global Fund to just 2 million doses over three years, and its licensing that excludes 26 middle-income countries has sparked criticism that profits trump public health. Gilead argues it is expanding access through generic licenses and deals with Global Fund and PEPFAR to deliver low- or no-profit supply, with a broader rollout planned in 2027 via generics in 120 countries, but concrete expansion remains uncertain.

via Los Angeles Times|
#access-to-medicines#business#gilead
Gilead urged to sell long-acting HIV prevention drug directly to MSF
health3 months ago

Gilead urged to sell long-acting HIV prevention drug directly to MSF

Doctors Without Borders (MSF) is pressing Gilead to directly sell lenacapavir, a two-a-year injectable PrEP for HIV prevention, to MSF for use in its humanitarian programs. Gilead has refused, directing MSF to obtain doses through the Global Fund, which has a limited supply, leaving many vulnerable people without access. MSF cites humanitarian need and calls for an urgent meeting by April 13 to decide pricing and delivery timelines.

via Doctors Without Borders|
#gilead#health#hivaids
Lenacapavir arrives in Eswatini as AIDS battle hinges on rollout
world3 months ago

Lenacapavir arrives in Eswatini as AIDS battle hinges on rollout

A new HIV prevention drug, lenacapavir, delivered as a twice-yearly injection, is being rolled out in Eswatini and nine high‑risk countries in a bid to end AIDS, described by UN officials as the closest thing to a vaccine. While it could dramatically reduce new infections if scaled globally, the rollout is hampered by years of foreign aid cuts that shuttered mobile clinics and constrained supply. The UN and Global Fund aim to reach millions, but plans to reach about two million people by 2028 fall well short of needs, underscoring the need for expanded funding and procurement to avoid repeating past delays that cost lives.

via The Independent|
#aids#eswatini#hiv
Zimbabwe rolls out lenacapavir HIV prevention, a new adherence-friendly approach
health4 months ago

Zimbabwe rolls out lenacapavir HIV prevention, a new adherence-friendly approach

Zimbabwe launched a national lenacapavir program, a twice-yearly injectable HIV prevention treatment that could replace daily PrEP pills. Funded by the U.S. government and the Global Fund, the initial rollout covers about 46,000 high-risk individuals across 24 sites, with priority for adolescent girls, young women and sex workers, as part of the country’s broader effort to curb HIV.

via africanews.com|
#global-fund#health#hiv
health9 months ago

South Africa's Health Minister Praises New HIV Prevention Jab Amid Supply Concerns

South Africa's health minister announced the introduction of lenacapavir, the world's first twice-yearly HIV prevention injection, with an initial limited supply of nearly half a million doses starting in April 2026, amid concerns over funding cuts and licensing issues affecting local manufacturing and access.

via ABC News - Breaking News, Latest News and Videos|
#global-health#health#hiv-prevention
Breaking Barriers to End HIV
health9 months ago

Breaking Barriers to End HIV

A new drug called lenacapavir, approved for HIV prevention, offers a twice-yearly injection with near-vaccine efficacy, potentially transforming HIV prevention efforts worldwide, especially in low-income countries, but its impact will depend heavily on political and logistical factors.

via vox.com|
#global-health#health#hiv