tldrdailynews.com logo
Tag

Gilead

All articles tagged with #gilead

Handmaid’s Tale Sequel Introduces a New Generation Inside Gilead
entertainment1 day ago

Handmaid’s Tale Sequel Introduces a New Generation Inside Gilead

THR previews The Testaments as a Hulu/MGM TV adaptation, with Bruce Miller reshaping Margaret Atwood’s sequel to fit a fresh TV timeline. The first season follows Daisy (Lucy Halliday), a Toronto teen entering Gilead as a Pearl Girl, and Agnes (Chase Infiniti), Hannah’s Gilead name, as they navigate Aunt Lydia’s elite academy and the regime’s oppression while June (Elisabeth Moss) quietly returns. With a ten-episode arc featuring a new generation (Becka, Shunammite, and others) the show expands the Handmaid’s Tale universe and arrives amid timely conversations about women’s autonomy.

via The Hollywood Reporter|
#bruce-miller#entertainment#gilead
Gilead's Lenacapavir Dilemma: A HIV Breakthrough Hindered by Access Rules
business2 days ago

Gilead's Lenacapavir Dilemma: A HIV Breakthrough Hindered by Access Rules

Lenacapavir could be a game-changer in HIV, but Gilead’s practice of not selling directly to Doctors Without Borders (MSF), limiting supply via the Global Fund to just 2 million doses over three years, and its licensing that excludes 26 middle-income countries has sparked criticism that profits trump public health. Gilead argues it is expanding access through generic licenses and deals with Global Fund and PEPFAR to deliver low- or no-profit supply, with a broader rollout planned in 2027 via generics in 120 countries, but concrete expansion remains uncertain.

via Los Angeles Times|
#access-to-medicines#business#gilead
Gilead urged to sell long-acting HIV prevention drug directly to MSF
health11 days ago

Gilead urged to sell long-acting HIV prevention drug directly to MSF

Doctors Without Borders (MSF) is pressing Gilead to directly sell lenacapavir, a two-a-year injectable PrEP for HIV prevention, to MSF for use in its humanitarian programs. Gilead has refused, directing MSF to obtain doses through the Global Fund, which has a limited supply, leaving many vulnerable people without access. MSF cites humanitarian need and calls for an urgent meeting by April 13 to decide pricing and delivery timelines.

via Doctors Without Borders|
#gilead#health#hivaids
Gilead to Acquire Ouro Medicines to Fast-Track T Cell Engager for Autoimmune Diseases
business18 days ago

Gilead to Acquire Ouro Medicines to Fast-Track T Cell Engager for Autoimmune Diseases

Gilead Sciences agreed to buy Ouro Medicines for $1.675 billion upfront plus up to $500 million in milestones to add OM336, a BCMAxCD3 T cell engager, to its inflammation portfolio. OM336 has shown rapid B cell depletion with a favorable safety profile in Phase 1/2 data and has FDA Fast Track and Orphan Drug designations, with registrational studies expected in 2027. Gilead is also in advanced talks for a collaboration with Galapagos, under which Galapagos would fund half of upfront and milestone payments, absorb Ouro’s operating assets, and receive 20-23% royalties on net sales while Gilead retains worldwide commercialization rights. The combined effort aims to accelerate immune-reset therapies for autoimmune diseases and potentially deliver durable, drug-free remission through BCMA-targeted T cell engagers.

via Business Wire|
#autoimmune-diseases#bcmaxcd3#business
Testaments Trailer Teases a New Generation of Gilead Survivors
tv1 month ago

Testaments Trailer Teases a New Generation of Gilead Survivors

Hulu releases the trailer for The Handmaid's Tale sequel The Testaments, set years after the original and following Agnes (Chase Infiniti) and Daisy as they navigate Aunt Lydia’s elite school and work to resist Gilead. The series premieres April 8 with three episodes, featuring Infiniti, Lucy Halliday and Ann Dowd among others, from creator Bruce Miller and producers MGM Television and 20th Television.

via Variety|
#gilead#handmaids-tale#the-testaments
Handmaid’s Tale Sequel Teases Teenage Rebellion in Gilead
tv1 month ago

Handmaid’s Tale Sequel Teases Teenage Rebellion in Gilead

THR unveils a first look at The Testaments, the Handmaid’s Tale sequel series on Hulu, described as a coming-of-age thriller set in Gilead. Taking place four years after the original, the show follows Agnes, the daughter of the heroine June Osborne, as she grows up under the regime and trains for life as a wife while a resistance movement gathers. Based on Margaret Atwood’s novel, The Testaments is from showrunner Bruce Miller with Ann Dowd returning as Aunt Lydia; Chase Infiniti leads the new cast. The series premieres April 8 with three episodes, followed by weekly episodes on Hulu and Disney+-bundled subscriptions.

via The Hollywood Reporter|
#coming-of-age#gilead#handmaids-tale
business1 month ago

Gilead to Acquire Arcellx for $7.8B to Accelerate Anito-cel and CAR-T Platform

Gilead will acquire Arcellx for $115 per share in cash plus a $5-per-share contingent value right (CVR), valuing the deal at about $7.8 billion and giving Gilead full control of Anito-cel, its BCMA-directed CAR-T therapy for multiple myeloma. The transaction aims to accelerate development and commercialization, with Anito-cel’s BLA accepted by the FDA and a PDUFA date of December 23, 2026; the deal is expected to close in Q2 2026 and to be accretive to EPS after FDA approval, with the CVR tied to cumulative global net sales milestones through 2029.

via Gilead Sciences|
#anito-cel#arcellx#business
‘The Handmaid’s Tale’ Concludes with Surprises and Farewells
television10 months ago

‘The Handmaid’s Tale’ Concludes with Surprises and Farewells

The series finale of Hulu’s The Handmaid’s Tale concludes the show after six seasons, but critics feel it lost its impact by the end, with unresolved plotlines, lack of consequences, and a focus on June that overshadowed the show's original themes. The finale hints at a possible adaptation of Margaret Atwood’s sequel, The Testaments, but leaves many questions open, reflecting on the show's decline in storytelling depth and tension.

via aftermath.site|
#adaptation#gilead#june