All articles tagged with #memory t cells
McGill researchers report that T cells can sense the stiffness of their surrounding tissue and use this mechanical information to bias their development into long-lasting tissue-resident memory cells, challenging the view that only biochemical cues guide immune memory and hinting at new approaches for autoimmune disease, cancer immunotherapy, and transplantation.
Research suggests that the human immune system is evolving to combat new SARS-CoV-2 variants, particularly after experiencing breakthrough infections by the omicron variant. Memory T cells formed after omicron breakthrough infection showed enhanced immunity against subsequent omicron variants, potentially preventing severe COVID-19 symptoms from future emerging variants. This finding may offer new perspectives in the era of COVID-19 endemic and could be applied to vaccine development to induce memory T cell defenses against subsequent variants.