Tag

Oral Delivery

All articles tagged with #oral delivery

business1 month ago•3 min saved

Novo Nordisk bets $2.1B on next-gen oral biologics with Vivtex

Novo Nordisk plans to invest up to $2.1 billion in Vivtex to advance next-generation oral delivery systems for biologics, leveraging Vivtex’s GI tract screening platform developed in MIT labs. Novo will fund research and later development and commercialization, aiming to expand its lead in oral obesity and diabetes therapies after Wegovy’s pill launch, while Vivtex pursues broad partnership opportunities and potential standalone programs.

via Fierce Biotech|

#biologics #business #novo-nordisk

health2 years ago•4 min saved

"Revolutionizing Drug Delivery: Hydrogels as Efficient Carriers"

Researchers at MIT have developed a new method for processing and delivering hydrophobic drugs, which are difficult to dissolve in water. The method involves dissolving the drug in a carrier solution and generating nanodroplets dispersed in a polymer solution. These nanodroplets are then gelled into a hydrogel, which holds the drug nanocrystals in place as the carrier evaporates. The hydrogel prevents the nanodroplets from merging together, resulting in uniform nanoparticles. This approach allows for precise control over drug release, including delayed and sequential release. The process shows promise for improving drug bioavailability and enabling the combination of multiple drugs in a single pill.

via Phys.org|

#drug-delivery #health #hydrogels

health2 years ago•4 min saved

Plant-based oral insulin delivery regulates blood sugar levels similarly to natural insulin with lower hypoglycemia risk.

Researchers at the University of Pennsylvania have developed a plant-based insulin that can be ingested orally and regulates blood sugar levels within 15 minutes of ingestion, similar to naturally secreted insulin. The insulin contains all three peptides that occur in natural insulin and is delivered to the liver via the gut-liver axis. The plant-based delivery system eliminates the need for expensive, complex laboratory equipment and results in a product that is shelf-stable at room temperature. The affordability and global access to healthcare are the foundation for the researchers' work.

via Penn Today|

#affordable-healthcare #diabetes #health