Tag

Organ Dysfunction

All articles tagged with #organ dysfunction

medical-research2 years ago•33 min saved

"Phoenix Criteria: A New Tool for Pediatric Sepsis Diagnosis"

A new study developed and validated the Phoenix Sepsis Score, a novel criteria for pediatric sepsis and septic shock based on organ dysfunction, using data from over 3.6 million pediatric encounters in 10 health systems. The Phoenix Sepsis Score outperformed existing organ dysfunction scores and the International Pediatric Sepsis Consensus Conference criteria, showing improved performance for diagnosing pediatric sepsis and septic shock across differently resourced settings. The study aims to provide improved criteria for identifying true-positive cases of pediatric sepsis while minimizing false-positive cases, with the goal of optimizing clinical care, research enrollment, and epidemiological surveillance.

via JAMA Network|

#international-pediatric-sepsis-consensus-conference #medical-research #organ-dysfunction

health2 years ago•3 min saved

Unveiling the Overlooked Role of Viral Pathogens in Sepsis

A study conducted by researchers at Brigham and Women's Hospital and Harvard Medical School highlights the importance of monitoring for sepsis in COVID-19 patients. The study found that SARS-CoV-2, the virus that causes COVID-19, contributed to a significant proportion of sepsis cases. The researchers emphasized the need for sepsis surveillance strategies that consider viral forms of sepsis and tailor diagnosis and treatment to each patient's syndrome and probable pathogen. The study also revealed that mortality rates for SARS-CoV-2-associated sepsis remained relatively high, underscoring the severity of the condition. The authors recommend watching for viral sepsis in hospitalized COVID-19 patients and considering potential viral culprits in patients who have already developed the complication.

via Forbes|

#covid-19 #health #hospital-surveillance

health2 years ago•2 min saved

The Pros and Cons of Frequent Marijuana Use for Diabetes and Weight Management

Frequent marijuana users are leaner and less likely to develop type two diabetes, but the pseudo-health benefit comes at a price, according to researchers at the University of California, Irvine. Adolescent mice given low doses of THC had reduced fat mass, increased lean mass, and were partially resistant to obesity and hyperglycemia. However, they also had a reduced ability to use fuel from fat stores, which can interfere with tasks like moving and thinking, and especially sustaining attention. The study found that THC use in adolescent mice resulted in reduced weight gain in both males and females, but further studies should look at other organ systems for potential THC-driven changes.

via Fortune|

#adolescent-mice #diabetes #health

health2 years ago•3 min saved

The Pros and Cons of Frequent Marijuana Use for Diabetes and Weight Management

Frequent marijuana users tend to be leaner and less likely to develop type two diabetes, but researchers at the University of California, Irvine, have found that the pseudo-health benefit comes at a price. Adolescent exposure to THC, the main psychoactive component of marijuana, may promote an enduring "pseudo-lean" state that superficially resembles healthy leanness but might, in fact, be rooted in organ dysfunction, according to the study. The study found that THC use in adolescent mice resulted in reduced weight gain in both males and females, but the study only focused on metabolic and molecular effects in males.

via Yahoo Finance|

#adolescent-exposure #diabetes #health