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Organ Sacks

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Secretive biotech envisions brainless 'organ sacks' for organs, prompting ethics questions
technology1 month ago

Secretive biotech envisions brainless 'organ sacks' for organs, prompting ethics questions

A hush-hush Silicon Valley startup, R3 Bio, has floated the idea of nanosentient/brainless 'organ sacks'—organs grown in a platform for implantation or drug testing—sparking bioethics concerns. After an interview where cofounder Alice Gilman described such concepts, she pushed to postpone the episode and hinted at government involvement, fueling scrutiny. Wired and MIT Technology Review subsequently explored the ambitions, while R3 Bio insisted it has no ongoing work in organ fabrication and aims to replace animal testing with cell-based methods. The public record remains murky on progress, and critics question the company’s transparency about what it’s actually doing.

Organs Without Brains: A Startup’s Bold Plan to Replace Animal Testing
science5 months ago

Organs Without Brains: A Startup’s Bold Plan to Replace Animal Testing

A Bay Area biotech startup, R3 Bio, backed by Immortal Dragons and billionaire Tim Draper, is pursuing nonsentient “organ sacks”—genetically engineered, brainless whole-organ systems—to replace animal testing and someday provide human tissues and organs. Initially targeting monkey organ sacks for toxicology testing, the company envisions using stem cells and gene editing to grow complex organ structures, addressing both ethical concerns with animal use and rising demand for organs amid shortages. Experts note the concept is theoretical and raise ethical questions about how such entities would be created, stored, or whether they could have awareness, but proponents argue the approach could offer a scalable alternative to current models. The effort aligns with a broader shift away from primate testing in the US and seeks to expand beyond testing to potential future replacement parts for humans.