Tag

Sex Hormones

All articles tagged with #sex hormones

When Language Meets Hormones: Bilingual Men Show Unexpected Dementia Protection
science1 month ago

When Language Meets Hormones: Bilingual Men Show Unexpected Dementia Protection

Canadian researchers analyzed data from 335 older adults with mild cognitive impairment and 170 with Alzheimer's from the COMPASS-ND cohort, finding that bilingualism interacts with verbal memory and sex hormones to influence brain resilience and dementia pathology; notably, bilingual men showed greater protection—potentially due to estradiol produced via aromatization alongside language experience—with higher resilience linked to better cognitive scores and lower neurodegeneration markers.

Hormones and bilingualism may bolster brain resilience against dementia
science1 month ago

Hormones and bilingualism may bolster brain resilience against dementia

Canadian COMPASS-ND data show that bilingualism, verbal memory and sex hormones interact to shape brain resilience and dementia risk: higher resilience links to lower dementia pathology and better cognition, with bilingual men showing notably greater protection; aromatization of testosterone to estradiol may boost verbal memory. The study calls for broader diagnostics beyond verbal memory and more research on how hormones influence aging brains.

The Impact of Sex Hormones on Alzheimer's and Menstrual Brain Changes
health2 years ago

The Impact of Sex Hormones on Alzheimer's and Menstrual Brain Changes

A study from the University of Western Ontario suggests that sex hormones, particularly estradiol, play a significant role in the development of Alzheimer's disease in the brain. Researchers found that the relationship between acetylcholine, a neurotransmitter essential for memory and cognition, and toxic amyloid was disrupted when estradiol was present. However, when sex hormones were eliminated, the relationship was connected, potentially increasing Alzheimer's pathology. As levels of estradiol decrease in postmenopausal women, this finding may help inform risk assessment and management strategies for Alzheimer's disease, particularly in perimenopausal women.