Pelacarsen's big failure rocks cardiology hopes

TL;DR Summary
Novartis announced that pelacarsen, an experimental drug designed to lower lipoprotein(a) and reduce risk of heart attack, stroke, and cardiovascular death, failed in a large clinical trial, delivering a shock to the field of cardiology and ending hopes for a new era in heart-disease prevention.
- Another Heart Drug Fails, Shocking Cardiologists The New York Times
- Novartis’ experimental cardiovascular drug fails a pivotal study STAT
- Novartis Drug Fails Key Test for New Heart Disease Approach Bloomberg.com
- Ionis partner Novartis announces Lp(a)HORIZON Phase 3 topline results for pelacarsen in patients with elevated Lp(a) and established cardiovascular disease (CVD) Business Wire
- Novartis announces Lp(a)HORIZON Phase III topline results GlobeNewswire
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