"Lyfgenia FDA Approval Sparks Competition in Sickle Cell Treatment Market"

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Source: STAT
"Lyfgenia FDA Approval Sparks Competition in Sickle Cell Treatment Market"
Photo: STAT
TL;DR

The FDA's approval of two gene therapies for sickle cell disease paves the way for competition between Bluebird Bio's Lyfgenia and the partnership of Vertex Pharmaceuticals and CRISPR Therapeutics' Casgevy. While Casgevy has the advantage of being a CRISPR-based therapy, some physicians and patients may prefer the lentiviral vector technology behind Lyfgenia, despite the added risk of blood cancer.

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