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Sickle Cell Disease

All articles tagged with #sickle cell disease

Illinois Expands Medical Cannabis Qualifying Conditions and Possession Rules
politics5 days ago

Illinois Expands Medical Cannabis Qualifying Conditions and Possession Rules

Illinois expanded its medical cannabis program by adding sickle cell disease and PMOS with chronic pain as qualifying conditions (bringing the total to 58). As part of SB 3222, adult‑use dispensaries can opt in to sell medical cannabis at the medical tax rate; adults may now possess up to 60 grams of flower, 10 grams of concentrates, and up to 1,000 mg of THC for medical patients. The law also doubles expungement eligibility for past convictions and tightens rules on hemp THC products. New qualifying conditions include female orgasmic disorder, endometriosis, ovarian cysts, and uterine fibroids, with Gov. Pritzker highlighting Illinois’ leadership on cannabis policy.

via Marijuana Moment|
#illinois#medical-cannabis#pmos
health-policy6 days ago

Illinois Expands Medical Cannabis Eligibility to Include PMOS and Sickle Cell Disease

IDPH adds polyendocrine metabolic ovarian syndrome (PMOS) with chronic pain and sickle cell disease to Illinois’ list of qualifying conditions for medical cannabis after review by the Medical Cannabis Advisory Board; the change, effective immediately, brings the total to 58 conditions and allows providers to certify patients right away.

via thexradio.com|
#health-policy#illinois#medical-cannabis
Gene Therapy Breakthrough Brings Hope to Black Americans Living With Sickle Cell
health2 months ago

Gene Therapy Breakthrough Brings Hope to Black Americans Living With Sickle Cell

A Louisiana man became the state’s first functionally cured sickle cell patient via 2023 FDA-approved gene therapies Casgevy and Lyfgenia; while these treatments hold promise for tens of thousands who are Black or African American, their high cost (around $2–$3 million) and limited treatment centers create access barriers, highlighting the need for broader insurance coverage, expanded care in underserved communities, and thorough discussion of risks like infertility and long‑term cancer risk.

via MS NOW|
#black-health#fda-approvals#gene-therapy
A Sickle Cell Breakthrough and the Peril of Political Attacks on Science
science2 months ago

A Sickle Cell Breakthrough and the Peril of Political Attacks on Science

A Louisiana man, Daniel Cressy, was functionally cured of sickle cell disease thanks to a breakthrough rooted in federally funded research, underscoring how modern medicine can dramatically improve lives—but the piece warns that Donald Trump’s anti-science stance could threaten such progress, which evolved from bone marrow transplants to newer therapies in the early 2010s.

via The Bulwark|
#bone-marrow-transplant#federal-funding#medical-breakthrough
Long Island Reports High Sickle Cell Burden, NYU Study Finds
health4 months ago

Long Island Reports High Sickle Cell Burden, NYU Study Finds

A NYU School of Global Public Health study of 42,200 sickle cell disease hospitalizations in New York (2009–2022) finds NYC has the most admissions, but Long Island has the highest share (10%) of hospitalizations with a major risk of death and the region incurs the highest total hospital charges. The study also shows rising rates of major severity (13% to 27%) and major mortality risk (3% to 13%), with COVID-19 likely contributing to the surge. Most hospitalized patients were Black (83%), and adults 18–29 accounted for 40%. The authors call for better access to specialists, improved pediatric-to-adult transition, and policy/funding efforts to reduce regional care gaps and emergency department burden.

via New York Post|
#health#hospitalizations#long-island
CRISPR-based sickle cell therapy earns $3M Breakthrough Prize for Thein and Orkin
health4 months ago

CRISPR-based sickle cell therapy earns $3M Breakthrough Prize for Thein and Orkin

Two researchers, Swee Lay Thein and Stuart Orkin, won the Breakthrough Prize in Life Sciences worth $3 million for work that led to Casgevy, a CRISPR-based therapy that functionally cures sickle cell disease and beta-thalassemia by disabling the BCL11A repressor to boost fetal hemoglobin. The treatment—developed with Vertex—involves editing a patient’s bone marrow cells and reinserting them, a costly, lengthy process with chemotherapy, and while a major milestone, access remains limited as scientists pursue in vivo approaches to broaden use.

via Live Science|
#bcl11a#beta-thalassemia#casgevy
Half-Matched Bone Marrow Transplant Brings Pain-Free Life to Sickle Cell Patient
health5 months ago

Half-Matched Bone Marrow Transplant Brings Pain-Free Life to Sickle Cell Patient

A woman diagnosed with sickle cell disease at 2 months old is cured after a haploidentical bone marrow transplant from her 50% genetic match at Johns Hopkins; she woke up pain-free the same day and by January 2025 was off pain medications, with doctors citing a 94% disease-free survival rate for this approach, signaling a potential cure for many sickle cell patients.

via Yahoo News Canada|
#disease-free-survival#haploidentical-bone-marrow-transplant#health
CRISPR breakthrough activates genes without DNA cuts
science7 months ago

CRISPR breakthrough activates genes without DNA cuts

Scientists at UNSW Sydney have developed a new CRISPR-based epigenetic editing technique that can turn genes on without cutting DNA, by removing chemical methyl groups that silence genes. This approach could lead to safer gene therapies for conditions like Sickle Cell disease, as it avoids the risks associated with DNA strand breaks. The research demonstrates that methylation directly controls gene activity and opens new possibilities for treating genetic disorders by reactivating silenced genes.

via ScienceDaily|
#crispr#dna-methylation#epigenetic-editing
Community Efforts and Advances in Sickle Cell Disease Awareness and Support
health11 months ago

Community Efforts and Advances in Sickle Cell Disease Awareness and Support

The article tells the story of Aiden-Jon Amir Hall, a young boy with sickle cell anaemia who passed away at age five, and his mother Latoya Minott Smikle's efforts to raise awareness and funds through the Aiden-Jon Amir Hall Foundation to support others affected by the disease, highlighting the challenges faced by families and the need for greater resources and support.

via Jamaica Observer|
#aiden-jon-amir-hall#awareness#foundation
Debate Over US Foreign Aid Cuts and Their Humanitarian Impact
world1 year ago

Debate Over US Foreign Aid Cuts and Their Humanitarian Impact

Mariam Mohammed blames U.S. aid cuts for her son Babagana's death in Nigeria, highlighting the human toll of reduced foreign assistance, despite claims by officials like Marco Rubio that no lives have been lost due to these cuts. The story underscores the impact on healthcare services in vulnerable regions and estimates suggest thousands have died as a result of aid reductions.

via NPR|
#babagana-mohammed#healthcare#nigeria