Common plastic additive may rewire the brain, triggering lifelong anxiety in rats

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Source: ScienceDaily
Common plastic additive may rewire the brain, triggering lifelong anxiety in rats
Photo: ScienceDaily
TL;DR

A study presented at ENDO 2026 reports that early-life exposure to the plasticizer DEHP increases anxiety-like behavior in adult male rats; exposure before and after birth led to less exploration and more freezing, and these effects were reversed by GABA agonists or testosterone, suggesting potential implications for human neurodevelopment and endocrine disruption.

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