Depression May Stop New Brain Cells From Forming in Adults, Altering Memory
TL;DR
A large Columbia-led study shows major depressive disorder disrupts neurogenesis in the adult hippocampus, potentially impairing pattern separation and the ability to store distinct memories. The researchers mapped widespread molecular and epigenetic changes across the hippocampal network, linking inflammation and altered gene programs to depression and suggesting new targets for treatments that classify depression by molecular subtype rather than brain region.
Topics:healthhealth-and-medicine#depression#health-and-medicine#hippocampus#memory#molecular-biology#neurogenesis
- Depression may shut down the brain’s ability to make new neurons Science Daily
- Neurogenesis stalls in the brains of adults with major depressive disorder, study shows News-Medical
- Depression doesn’t shrink the brain like we thought it did New Scientist
- Dysregulated adult hippocampal neurogenesis in major depressive disorders Nature
- "Why can't I keep getting out of my negative thoughts?"Brain science experts gave biological answers.. 매일경제
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