Long COVID Symptoms Linked to Mood-Processing Brain Activity, Not Widespread Inflammation

TL;DR Summary
A University of Turku study using PET and MRI found no evidence of widespread brain inflammation in long COVID patients compared with healthy controls. Inflammation may be higher earlier after infection and fade over time. More severe symptoms correlated with increased activity in emotion-related regions (hippocampus and amygdala), suggesting treatments focusing on stress management and emotional regulation rather than solely anti-inflammatory approaches.
- Scientists thought brain inflammation was driving long COVID but the scans told a different story ScienceDaily
- Brain inflammation is unlikely to explain persistent long COVID symptoms The National Law Review
- Long COVID May Affect Emotional Brain Regions More Than Brain Inflammation, Study Suggests The Indian Practitioner
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