GLP-1 diabetes medicines show potential to curb Alzheimer's protein buildup in preclinical studies

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Source: ScienceAlert
GLP-1 diabetes medicines show potential to curb Alzheimer's protein buildup in preclinical studies
Photo: ScienceAlert
TL;DR

A new review of mostly preclinical studies links GLP-1 diabetes/weight-loss medications (e.g., semaglutide, liraglutide) to reduced amyloid-beta plaques and tau tangles in cells and animals, with only two small human trials reporting mixed results; still early evidence and larger clinical trials are needed to confirm cognitive benefits.

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